Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells

Atypical teratoid/rhabdoid tumor (ATRT) is a malignant pediatric brain tumor with great recurrence after complete surgery and chemotherapy. Here, we demonstrate that cisplatin treatment selects not only for resistance but also for a more oncogenic phenotype characterized by high self-renewal and inv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Wei-Hsiu, Chen, Ming-Teh, Wang, Mong-Lien, Lee, Yi-Yen, Chiou, Guang-Yuh, Chien, Chian-Shiu, Huang, Pin-I, Chen, Yi-Wei, Huang, Ming-Chao, Chiou, Shih-Hwa, Shih, Yang-Hsin, Ma, Hsin-I
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359329/
https://ncbi.nlm.nih.gov/pubmed/25638155
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