In vivo function of the lipid raft protein flotillin 1 during CD8(+) T cell-mediated host surveillance

Flotillin-1 (Flot1) is an evolutionary conserved, ubiquitously expressed lipid raft-associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired due to a decrease in myosin II-mediated contractility. Flot1 also accumulates in the uropod of polarized T cells, suggesting an ana...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Ficht, Xenia, Ruef, Nora, Stolp, Bettina, Samson, Guerric P.B., Moalli, Federica, Page, Nicolas, Merkler, Doron, Nichols, Ben J., Diz-Muñoz, Alba, Legler, Daniel F., Niggli, Verena, Stein, Jens V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820809/
https://ncbi.nlm.nih.gov/pubmed/31548330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900075
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