The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8(+) T cells

T cells are actively scanning pMHC-presenting cells in lymphoid organs and nonlymphoid tissues (NLTs) with divergent topologies and confinement. How the T cell actomyosin cytoskeleton facilitates this task in distinct environments is incompletely understood. Here, we show that lack of Myosin IXb (My...

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發表在:J Exp Med
Main Authors: Moalli, Federica, Ficht, Xenia, Germann, Philipp, Vladymyrov, Mykhailo, Stolp, Bettina, de Vries, Ingrid, Lyck, Ruth, Balmer, Jasmin, Fiocchi, Amleto, Kreutzfeldt, Mario, Merkler, Doron, Iannacone, Matteo, Ariga, Akitaka, Stoffel, Michael H., Sharpe, James, Bähler, Martin, Sixt, Michael, Diz-Muñoz, Alba, Stein, Jens V.
格式: Artigo
語言:Inglês
出版: Rockefeller University Press 2018
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028505/
https://ncbi.nlm.nih.gov/pubmed/29875261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170896
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