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In vivo function of the lipid raft protein flotillin 1 during CD8(+) T cell-mediated host surveillance
Flotillin-1 (Flot1) is an evolutionary conserved, ubiquitously expressed lipid raft-associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired due to a decrease in myosin II-mediated contractility. Flot1 also accumulates in the uropod of polarized T cells, suggesting an ana...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820809/ https://ncbi.nlm.nih.gov/pubmed/31548330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900075 |
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