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Dynamic Emergence of Observed and Hidden Intra-tumor Heterogeneity
Intra-tumor heterogeneity is frequently observed in cancer patients, and it is associated with therapeutic resistance and disease relapse. However, its systematic assessment is still limited and often unfeasible. Here, we use a mathematical model of tumor progression to decipher how multiple clones...
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| Publicado no: | iScience |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820272/ https://ncbi.nlm.nih.gov/pubmed/31655256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.10.018 |
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