Intra-tumor Genetic Heterogeneity in Rectal Cancer

Colorectal cancer arises in part from the cumulative effects of multiple gene lesions. Recent studies in selected cancer types have revealed significant intra-tumor genetic heterogeneity and highlighted its potential role in disease progression and resistance to therapy. We hypothesized the existenc...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Hardiman, Karin M., Ulintz, Peter J., Kuick, Rork, Hovelson, Daniel H., Gates, Christopher M., Bhasi, Ashwini, Grant, Ana Rodrigues, Liu, Jianhua, Cani, Andi K., Greenson, Joel, Tomlins, Scott, Fearon, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695247/
https://ncbi.nlm.nih.gov/pubmed/26568296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.131
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