Intra-Tumoral Genomic Heterogeneity in Rectal Cancer: Mutational Status Is Dependent on Preoperative Biopsy Depth and Location

SIMPLE SUMMARY: A subset of patients with rectal cancer are treated before surgery with chemoradiation. Unfortunately, this neoadjuvant chemoradiotherapy does not have the preferred effect of tumor downstaging in all patients, but does bring substantial side effects and possible complications. A pre...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Vuijk, Floris A., van de Water, Carlijn, Lent-van Vliet, Shannon, van der Valk, Maxime J. M., Simmer, Femke, van de Velde, Cornelis J. H., Vahrmeijer, Alexander L., Nagtegaal, Iris D., Hilling, Denise E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125993/
https://ncbi.nlm.nih.gov/pubmed/34065112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092271
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