Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury

Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinoma, and neurovisceral involvement, including seizur...

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Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Maitra, Dhiman, Bragazzi Cunha, Juliana, Elenbaas, Jared S., Bonkovsky, Herbert L., Shavit, Jordan A., Omary, M. Bishr
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820234/
https://ncbi.nlm.nih.gov/pubmed/31233899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.06.006
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