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Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury

Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinoma, and neurovisceral involvement, including seizur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Gastroenterol Hepatol
Hauptverfasser: Maitra, Dhiman, Bragazzi Cunha, Juliana, Elenbaas, Jared S., Bonkovsky, Herbert L., Shavit, Jordan A., Omary, M. Bishr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820234/
https://ncbi.nlm.nih.gov/pubmed/31233899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.06.006
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