The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD

The BMRF1 protein of Epstein-Barr virus (EBV) has multiple roles in viral lytic infection, including serving as the DNA polymerase processivity factor, activating transcription from several EBV promoters and inhibiting the host DNA damage response to double-stranded DNA breaks (DSBs). Using affinity...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Salamun, Samuel G., Sitz, Justine, De La Cruz-Herrera, Carlos F., Yockteng-Melgar, Jaime, Marcon, Edyta, Greenblatt, Jack, Fradet-Turcotte, Amelie, Frappier, Lori
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819917/
https://ncbi.nlm.nih.gov/pubmed/31462557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01070-19
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