The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD

The BMRF1 protein of Epstein-Barr virus (EBV) has multiple roles in viral lytic infection, including serving as the DNA polymerase processivity factor, activating transcription from several EBV promoters and inhibiting the host DNA damage response to double-stranded DNA breaks (DSBs). Using affinity...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Salamun, Samuel G., Sitz, Justine, De La Cruz-Herrera, Carlos F., Yockteng-Melgar, Jaime, Marcon, Edyta, Greenblatt, Jack, Fradet-Turcotte, Amelie, Frappier, Lori
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819917/
https://ncbi.nlm.nih.gov/pubmed/31462557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01070-19
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