An Equine Herpesvirus Type 1 (EHV-1) Ab4 Open Reading Frame 2 Deletion Mutant Provides Immunity and Protection from EHV-1 Infection and Disease

Equine herpesvirus type 1 (EHV-1) outbreaks continue to occur despite widely used vaccination. Therefore, development of EHV-1 vaccines providing improved immunity and protection is ongoing. Here, an open reading frame 2 deletion mutant of the neuropathogenic EHV-1 strain Ab4 (Ab4ΔORF2) was tested a...

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Vydáno v:J Virol
Hlavní autoři: Schnabel, Christiane L., Babasyan, Susanna, Rollins, Alicia, Freer, Heather, Wimer, Christine L., Perkins, Gillian A., Raza, Fahad, Osterrieder, Nikolaus, Wagner, Bettina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819910/
https://ncbi.nlm.nih.gov/pubmed/31462575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01011-19
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