Selective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of d-serine within the mouse cerebellum

BACKGROUND: Programmed epigenetic modifications occurring at early postnatal brain developmental stages may have a long-lasting impact on brain function and complex behavior throughout life. Notably, it is now emerging that several genes that undergo perinatal changes in DNA methylation are associat...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Cuomo, Mariella, Keller, Simona, Punzo, Daniela, Nuzzo, Tommaso, Affinito, Ornella, Coretti, Lorena, Carella, Massimo, de Rosa, Valeria, Florio, Ermanno, Boscia, Francesca, Avvedimento, Vittorio Enrico, Cocozza, Sergio, Errico, Francesco, Usiello, Alessandro, Chiariotti, Lorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819446/
https://ncbi.nlm.nih.gov/pubmed/31661019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0732-z
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