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Modeling DNA methylation by analyzing the individual configurations of single molecules

DNA methylation is often analyzed by reporting the average methylation degree of each cytosine. In this study, we used a single molecule methylation analysis in order to look at the methylation conformation of individual molecules. Using D-aspartate oxidase as a model gene, we performed an in-depth...

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Détails bibliographiques
Publié dans:Epigenetics
Auteurs principaux: Affinito, Ornella, Scala, Giovanni, Palumbo, Domenico, Florio, Ermanno, Monticelli, Antonella, Miele, Gennaro, Avvedimento, Vittorio Enrico, Usiello, Alessandro, Chiariotti, Lorenzo, Cocozza, Sergio
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193494/
https://ncbi.nlm.nih.gov/pubmed/27748645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1246108
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