The Emerging Role of Altered d-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies

Por Errico, Francesco, Nuzzo, Tommaso, Carella, Massimo, Bertolino, Alessandro, Usiello, Alessandro
Publicado no Front Psychiatry (2018)

Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients

Por Nuzzo, Tommaso, Sacchi, Silvia, Errico, Francesco, Keller, Simona, Palumbo, Orazio, Florio, Ermanno, Punzo, Daniela, Napolitano, Francesco, Copetti, Massimiliano, Carella, Massimo, Chiariotti, Lorenzo, Bertolino, Alessandro, Pollegioni, Loredano, Usiello, Alessandro
Publicado no NPJ Schizophr (2017)

Selective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of d-serine within the mouse cerebellum

Por Cuomo, Mariella, Keller, Simona, Punzo, Daniela, Nuzzo, Tommaso, Affinito, Ornella, Coretti, Lorena, Carella, Massimo, de Rosa, Valeria, Florio, Ermanno, Boscia, Francesca, Avvedimento, Vittorio Enrico, Cocozza, Sergio, Errico, Francesco, Usiello, Alessandro, Chiariotti, Lorenzo
Publicado no Clin Epigenetics (2019)

Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity

Por Sacchi, Silvia, Novellis, Vito De, Paolone, Giovanna, Nuzzo, Tommaso, Iannotta, Monica, Belardo, Carmela, Squillace, Marta, Bolognesi, Paolo, Rosini, Elena, Motta, Zoraide, Frassineti, Martina, Bertolino, Alessandro, Pollegioni, Loredano, Morari, Michele, Maione, Sabatino, Errico, Francesco, Usiello, Alessandro
Publicado no Sci Rep (2017)

The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson’s disease patients

Por Nuzzo, Tommaso, Punzo, Daniela, Devoto, Paola, Rosini, Elena, Paciotti, Silvia, Sacchi, Silvia, Li, Qin, Thiolat, Marie-Laure, Véga, Celine, Carella, Massimo, Carta, Manolo, Gardoni, Fabrizio, Calabresi, Paolo, Pollegioni, Loredano, Bezard, Erwan, Parnetti, Lucilla, Errico, Francesco, Usiello, Alessandro
Publicado no Sci Rep (2019)

RasGRP1 is a causal factor in the development of l-DOPA–induced dyskinesia in Parkinson’s disease

Por Eshraghi, Mehdi, Ramírez-Jarquín, Uri Nimrod, Shahani, Neelam, Nuzzo, Tommaso, De Rosa, Arianna, Swarnkar, Supriya, Galli, Nicole, Rivera, Oscar, Tsaprailis, George, Scharager-Tapia, Catherina, Crynen, Gogce, Li, Qin, Thiolat, Marie-Laure, Bezard, Erwan, Usiello, Alessandro, Subramaniam, Srinivasa
Publicado no Sci Adv (2020)

The striatal-enriched protein Rhes is a critical modulator of cocaine-induced molecular and behavioral responses

Por Napolitano, Francesco, De Rosa, Arianna, Russo, Rosita, Di Maio, Anna, Garofalo, Martina, Federici, Mauro, Migliarini, Sara, Ledonne, Ada, Rizzo, Francesca Romana, Avallone, Luigi, Nuzzo, Tommaso, Biagini, Tommaso, Pasqualetti, Massimo, Mercuri, Nicola Biagio, Mazza, Tommaso, Chambery, Angela, Usiello, Alessandro
Publicado no Sci Rep (2019)

Age-Related Changes in d-Aspartate Oxidase Promoter Methylation Control Extracellular d-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging

Por Punzo, Daniela, Errico, Francesco, Cristino, Luigia, Sacchi, Silvia, Keller, Simona, Belardo, Carmela, Luongo, Livio, Nuzzo, Tommaso, Imperatore, Roberta, Florio, Ermanno, De Novellis, Vito, Affinito, Ornella, Migliarini, Sara, Maddaloni, Giacomo, Sisalli, Maria Josè, Pasqualetti, Massimo, Pollegioni, Loredano, Maione, Sabatino, Chiariotti, Lorenzo, Usiello, Alessandro
Publicado no J Neurosci (2016)