Nuclear envelope–localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

Deciphering novel pathways that regulate liver lipid content has profound implications for understanding the pathophysiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Recent evidence suggests that the nuclear envelope is a site of regulation of lipid metabo...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Shin, Ji-Yeon, Hernandez-Ono, Antonio, Fedotova, Tatyana, Östlund, Cecilia, Lee, Michael J., Gibeley, Sarah B., Liang, Chun-Chi, Dauer, William T., Ginsberg, Henry N., Worman, Howard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819140/
https://ncbi.nlm.nih.gov/pubmed/31408437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129769
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