Nuclear envelope–localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

Deciphering novel pathways that regulate liver lipid content has profound implications for understanding the pathophysiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Recent evidence suggests that the nuclear envelope is a site of regulation of lipid metabo...

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Udgivet i:J Clin Invest
Main Authors: Shin, Ji-Yeon, Hernandez-Ono, Antonio, Fedotova, Tatyana, Östlund, Cecilia, Lee, Michael J., Gibeley, Sarah B., Liang, Chun-Chi, Dauer, William T., Ginsberg, Henry N., Worman, Howard J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819140/
https://ncbi.nlm.nih.gov/pubmed/31408437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129769
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