Nuclear envelope–localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

Deciphering novel pathways that regulate liver lipid content has profound implications for understanding the pathophysiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Recent evidence suggests that the nuclear envelope is a site of regulation of lipid metabo...

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Vydáno v:J Clin Invest
Hlavní autoři: Shin, Ji-Yeon, Hernandez-Ono, Antonio, Fedotova, Tatyana, Östlund, Cecilia, Lee, Michael J., Gibeley, Sarah B., Liang, Chun-Chi, Dauer, William T., Ginsberg, Henry N., Worman, Howard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819140/
https://ncbi.nlm.nih.gov/pubmed/31408437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129769
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