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Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis
Fibronectin in the vascular wall promotes inflammatory activation of the endothelium during vascular remodeling and atherosclerosis. These effects are mediated in part by fibronectin binding to integrin α5, which recruits and activates phosphodiesterase 4D5 (PDE4D5) by inducing its dephosphorylation...
Tallennettuna:
| Julkaisussa: | J Clin Invest |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Clinical Investigation
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6819111/ https://ncbi.nlm.nih.gov/pubmed/31408443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127692 |
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