Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice

Type 2 diabetes (T2D) has become a major health problem worldwide. Skeletal muscle (SKM) is the key tissue for whole-body glucose disposal and utilization. New drugs aimed at improving insulin sensitivity of SKM would greatly expand available therapeutic options. β-arrestin-1 and -2 (Barr1 and Barr2...

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Udgivet i:PLoS Genet
Main Authors: Meister, Jaroslawna, Bone, Derek B. J., Godlewski, Grzegorz, Liu, Ziyi, Lee, Regina J., Vishnivetskiy, Sergey A., Gurevich, Vsevolod V., Springer, Danielle, Kunos, George, Wess, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818801/
https://ncbi.nlm.nih.gov/pubmed/31622341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008424
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