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Enhanced Phosphorylation-Independent Arrestins and Gene Therapy
A variety of heritable and acquired disorders is associated with excessive signaling by mutant or overstimulated GPCRs. Since any conceivable treatment of diseases caused by gain-of-function mutations requires gene transfer, one possible approach is functional compensation. Several structurally dist...
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| Publicat a: | Handb Exp Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516159/ https://ncbi.nlm.nih.gov/pubmed/24292828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-41199-1_7 |
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