APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy

African polymorphisms in the gene for Apolipoprotein L1 (APOL1) confer a survival advantage against lethal trypanosomiasis but also an increased risk for several chronic kidney diseases (CKD) including HIV-associated nephropathy (HIVAN). APOL1 is expressed in renal cells, however, the pathogenic eve...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Bruggeman, Leslie A., Wu, Zhenzhen, Luo, Liping, Madhavan, Sethu, Drawz, Paul E., Thomas, David B., Barisoni, Laura, O'Toole, John F., Sedor, John R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818796/
https://ncbi.nlm.nih.gov/pubmed/31661509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224408
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