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ApoL1 Overexpression Drives Variant-Independent Cytotoxicity
Coding variants in the APOL1 gene are associated with kidney diseases in African ancestral populations; yet, the underlying biologic mechanisms remain uncertain. Variant-dependent autophagic and cytotoxic cell death have been proposed as pathogenic pathways mediating kidney injury. To examine this p...
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| Publicado en: | J Am Soc Nephrol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827587/ https://ncbi.nlm.nih.gov/pubmed/29180397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016121322 |
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