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APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy
African polymorphisms in the gene for Apolipoprotein L1 (APOL1) confer a survival advantage against lethal trypanosomiasis but also an increased risk for several chronic kidney diseases (CKD) including HIV-associated nephropathy (HIVAN). APOL1 is expressed in renal cells, however, the pathogenic eve...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818796/ https://ncbi.nlm.nih.gov/pubmed/31661509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224408 |
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