Cell generation dynamics underlying naive T-cell homeostasis in adult humans

Thymic involution and proliferation of naive T cells both contribute to shaping the naive T-cell repertoire as humans age, but a clear understanding of the roles of each throughout a human life span has been difficult to determine. By measuring nuclear bomb test–derived (14)C in genomic DNA, we dete...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Mold, Jeff E., Réu, Pedro, Olin, Axel, Bernard, Samuel, Michaëlsson, Jakob, Rane, Sanket, Yates, Andrew, Khosravi, Azadeh, Salehpour, Mehran, Possnert, Göran, Brodin, Petter, Frisén, Jonas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818757/
https://ncbi.nlm.nih.gov/pubmed/31661488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000383
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