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Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq
Cellular heterogeneity can emerge from the expression of only one parental allele. However, it has remained controversial whether, or to what degree, random monoallelic expression of autosomal genes (aRME) is mitotically inherited (clonal) or stochastic (dynamic) in somatic cells, particularly in vi...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117254/ https://ncbi.nlm.nih.gov/pubmed/27668657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3678 |
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