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Preformulation and Evaluation of Tofacitinib as a Therapeutic Treatment for Asthma

Preformulation studies on tofacitinib citrate, a small molecule JAK3 specific inhibitor, have not been previously reported in literature. We therefore conducted several preformulation studies on tofacitinib citrate, and its free base, to better understand factors that affect its solubility, stabilit...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Younis, Usir S., Vallorz, Ernest, Addison, Kenneth J., Ledford, Julie G., Myrdal, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818719/
https://ncbi.nlm.nih.gov/pubmed/30993508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-019-1377-0
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