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Genetic Variation in Surfactant Protein A2 Delays Resolution of Eosinophilia in Asthma
Surfactant protein-A (SP-A) is an important mediator of pulmonary immunity. A specific genetic variation in SP-A2, corresponding to a glutamine (Q) to lysine (K) amino acid substitution at position 223 of the lectin domain, was shown to alter the ability of SP-A to inhibit eosinophil degranulation....
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| Vydáno v: | J Immunol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702058/ https://ncbi.nlm.nih.gov/pubmed/31350355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900546 |
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