Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments

The construction of genome-wide mutant collections has enabled high-throughput, high-dimensional quantitative characterization of gene and chemical function, particularly via genetic and chemical-genetic interaction experiments. As the throughput of these experiments increases with improvements in s...

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Veröffentlicht in:Nat Protoc
Hauptverfasser: Simpkins, Scott W., Deshpande, Raamesh, Nelson, Justin, Li, Sheena C., Piotrowski, Jeff S., Ward, Henry Neil, Yashiroda, Yoko, Osada, Hiroyuki, Yoshida, Minoru, Boone, Charles, Myers, Chad L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818255/
https://ncbi.nlm.nih.gov/pubmed/30635653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0099-1
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