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Force-Dependent Facilitated Dissociation Can Generate Protein-DNA Catch Bonds
Cellular structures are continually subjected to forces, which may serve as mechanical signals for cells through their effects on biomolecule interaction kinetics. Typically, molecular complexes interact via “slip bonds,” so applied forces accelerate off rates by reducing transition energy barriers....
Guardat en:
| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818169/ https://ncbi.nlm.nih.gov/pubmed/31427067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.044 |
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