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Force-Dependent Facilitated Dissociation Can Generate Protein-DNA Catch Bonds

Cellular structures are continually subjected to forces, which may serve as mechanical signals for cells through their effects on biomolecule interaction kinetics. Typically, molecular complexes interact via “slip bonds,” so applied forces accelerate off rates by reducing transition energy barriers....

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Dahlke, Katelyn, Zhao, Jing, Sing, Charles E., Banigan, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818169/
https://ncbi.nlm.nih.gov/pubmed/31427067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.044
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