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Force-Dependent Facilitated Dissociation Can Generate Protein-DNA Catch Bonds

Cellular structures are continually subjected to forces, which may serve as mechanical signals for cells through their effects on biomolecule interaction kinetics. Typically, molecular complexes interact via “slip bonds,” so applied forces accelerate off rates by reducing transition energy barriers....

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Vydáno v:Biophys J
Hlavní autoři: Dahlke, Katelyn, Zhao, Jing, Sing, Charles E., Banigan, Edward J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818169/
https://ncbi.nlm.nih.gov/pubmed/31427067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.044
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