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Force-Dependent Facilitated Dissociation Can Generate Protein-DNA Catch Bonds

Cellular structures are continually subjected to forces, which may serve as mechanical signals for cells through their effects on biomolecule interaction kinetics. Typically, molecular complexes interact via “slip bonds,” so applied forces accelerate off rates by reducing transition energy barriers....

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Dahlke, Katelyn, Zhao, Jing, Sing, Charles E., Banigan, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818169/
https://ncbi.nlm.nih.gov/pubmed/31427067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.044
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