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Regulation of Catch Bonds by Rate of Force Application

The current paradigm for receptor-ligand dissociation kinetics assumes off-rates as functions of instantaneous force without impact from its prior history. This a priori assumption is the foundation for predicting dissociation from a given initial state using kinetic equations. Here we have invalida...

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Main Authors: Sarangapani, Krishna K., Qian, Jin, Chen, Wei, Zarnitsyna, Veronika I., Mehta, Padmaja, Yago, Tadayuki, McEver, Rodger P., Zhu, Cheng
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173187/
https://ncbi.nlm.nih.gov/pubmed/21775439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.240044
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