Differential regulation of Ca(2+) influx by ORAI channels mediates enamel mineralization

Store-operated Ca(2+) entry (SOCE) channels are highly selective Ca(2+) channels activated by the endoplasmic reticulum (ER) sensors STIM1 and STIM2. Their direct interaction with the pore-forming plasma membrane ORAI proteins (ORAI1, ORAI2, and ORAI3) leads to sustained Ca(2+) fluxes that are criti...

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Bibliografske podrobnosti
izdano v:Sci Signal
Main Authors: Eckstein, Miriam, Vaeth, Martin, Aulestia, Francisco J., Costiniti, Veronica, Kassam, Serena N., Bromage, Timothy G., Pedersen, Pal, Issekutz, Thomas, Idaghdour, Youssef, Moursi, Amr M., Feske, Stefan, Lacruz, Rodrigo S.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818134/
https://ncbi.nlm.nih.gov/pubmed/31015290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aav4663
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