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Differential regulation of Ca(2+) influx by ORAI channels mediates enamel mineralization
Store-operated Ca(2+) entry (SOCE) channels are highly selective Ca(2+) channels activated by the endoplasmic reticulum (ER) sensors STIM1 and STIM2. Their direct interaction with the pore-forming plasma membrane ORAI proteins (ORAI1, ORAI2, and ORAI3) leads to sustained Ca(2+) fluxes that are criti...
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| Udgivet i: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818134/ https://ncbi.nlm.nih.gov/pubmed/31015290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aav4663 |
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