High immune cytolytic activity in tumor‐free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue

Immune cells and cytolytic activity within the tumor microenvironment are being intensively studied. Through transcriptome profiling, immune cell enumeration using the xCell tool and cytolytic activity quantification according to granzyme A (GZMA) and perforin (PRF1) mRNA levels, we investigated imm...

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Vydáno v:J Pathol Clin Res
Hlavní autoři: Gu, Xiaolian, Boldrup, Linda, Coates, Philip J, Fahraeus, Robin, Wang, Lixiao, Wilms, Torben, Norberg‐Spaak, Lena, Sgaramella, Nicola, Nylander, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817829/
https://ncbi.nlm.nih.gov/pubmed/31237113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.138
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