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High immune cytolytic activity in tumor‐free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue

Immune cells and cytolytic activity within the tumor microenvironment are being intensively studied. Through transcriptome profiling, immune cell enumeration using the xCell tool and cytolytic activity quantification according to granzyme A (GZMA) and perforin (PRF1) mRNA levels, we investigated imm...

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Detalhes bibliográficos
Publicado no:J Pathol Clin Res
Main Authors: Gu, Xiaolian, Boldrup, Linda, Coates, Philip J, Fahraeus, Robin, Wang, Lixiao, Wilms, Torben, Norberg‐Spaak, Lena, Sgaramella, Nicola, Nylander, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817829/
https://ncbi.nlm.nih.gov/pubmed/31237113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.138
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