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High immune cytolytic activity in tumor‐free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue

Immune cells and cytolytic activity within the tumor microenvironment are being intensively studied. Through transcriptome profiling, immune cell enumeration using the xCell tool and cytolytic activity quantification according to granzyme A (GZMA) and perforin (PRF1) mRNA levels, we investigated imm...

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Détails bibliographiques
Publié dans:J Pathol Clin Res
Auteurs principaux: Gu, Xiaolian, Boldrup, Linda, Coates, Philip J, Fahraeus, Robin, Wang, Lixiao, Wilms, Torben, Norberg‐Spaak, Lena, Sgaramella, Nicola, Nylander, Karin
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817829/
https://ncbi.nlm.nih.gov/pubmed/31237113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.138
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