High immune cytolytic activity in tumor‐free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue

Immune cells and cytolytic activity within the tumor microenvironment are being intensively studied. Through transcriptome profiling, immune cell enumeration using the xCell tool and cytolytic activity quantification according to granzyme A (GZMA) and perforin (PRF1) mRNA levels, we investigated imm...

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Bibliographic Details
Published in:J Pathol Clin Res
Main Authors: Gu, Xiaolian, Boldrup, Linda, Coates, Philip J, Fahraeus, Robin, Wang, Lixiao, Wilms, Torben, Norberg‐Spaak, Lena, Sgaramella, Nicola, Nylander, Karin
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817829/
https://ncbi.nlm.nih.gov/pubmed/31237113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.138
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