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High immune cytolytic activity in tumor‐free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue

Immune cells and cytolytic activity within the tumor microenvironment are being intensively studied. Through transcriptome profiling, immune cell enumeration using the xCell tool and cytolytic activity quantification according to granzyme A (GZMA) and perforin (PRF1) mRNA levels, we investigated imm...

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Dettagli Bibliografici
Pubblicato in:J Pathol Clin Res
Autori principali: Gu, Xiaolian, Boldrup, Linda, Coates, Philip J, Fahraeus, Robin, Wang, Lixiao, Wilms, Torben, Norberg‐Spaak, Lena, Sgaramella, Nicola, Nylander, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817829/
https://ncbi.nlm.nih.gov/pubmed/31237113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.138
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