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Long and Repeat-Rich Intronic Sequences Favor Circular RNA Formation under Conditions of Reduced Spliceosome Activity

Circular RNAs (circRNAs), an important class of regulatory RNAs, have been shown to be the most prevalent in the brain compared with other tissues. However the processes governing their biogenesis in neurons are still elusive. Moreover, little is known about whether and how different biogenesis fact...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Wang, Mantian, Hou, Jingyi, Müller-McNicoll, Michaela, Chen, Wei, Schuman, Erin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817660/
https://ncbi.nlm.nih.gov/pubmed/31590076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.08.058
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