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Diverse Folding Pathways of HIV-1 Protease Monomer on a Rugged Energy Landscape

The modern energy landscape theory of protein folding predicts multiple folding pathways connecting a myriad of unfolded conformations and a well-defined folded state. However, direct experimental observation of heterogeneous folding pathways is difficult. Naturally evolved proteins typically exhibi...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Yoo, Janghyun, Louis, John M., Chung, Hoi Sung
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817636/
https://ncbi.nlm.nih.gov/pubmed/31587829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.09.015
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