ロード中...
Evolution under drug pressure remodels the folding free-energy landscape of mature HIV-1 protease
Using high-pressure NMR spectroscopy and differential scanning calorimetry, we investigate the folding landscape of the mature HIV-1 protease homodimer. The cooperativity of unfolding was measured in the absence or presence of an active site inhibitor DMP323, for the active protease (PR), its inacti...
保存先:
| 出版年: | J Mol Biol |
|---|---|
| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905781/ https://ncbi.nlm.nih.gov/pubmed/27170547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.05.005 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|