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Pressure-induced structural transition of mature HIV-1 Protease from a combined NMR/MD simulation approach
We investigate the pressure-induced structural changes in the mature human immunodeficiency virus type 1 protease dimer (HIV-1 PR), using residual dipolar coupling (RDC) measurements in a weakly oriented solution. (1)D(NH) RDCs were measured under high-pressure conditions for an inhibitor-free PR an...
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| Publicado no: | Proteins |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715683/ https://ncbi.nlm.nih.gov/pubmed/26385843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24931 |
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