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Impact of Hydrostatic Pressure on an Intrinsically Disordered Protein: A High-Pressure NMR Study of α-Synuclein [a]

The impact of pressure on the backbone (15)N, (1)H and (13)C chemical shifts in N-terminally acetylated α-synuclein has been evaluated over a pressure range spanning from 1–2500 bar. Even while the chemical shifts fall very close to random coil values, as expected for an intrinsically disordered pro...

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Detalhes bibliográficos
Main Authors: Roche, Julien, Ying, Jinfa, Maltsev, Alexander S., Bax, Ad
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874805/
https://ncbi.nlm.nih.gov/pubmed/23813793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300244
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