Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells

Therapeutic effects of FLT3 inhibitors have been reported in acute myeloid leukemia (AML) with constitutively activating FLT3 mutations, including internal tandem duplication (ITD) and point mutation, which are found in approximately one-third of AML patients. One of the critical issues of treatment...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Kawase, Tatsuya, Nakazawa, Taisuke, Eguchi, Tomohiro, Tsuzuki, Hirofumi, Ueno, Yoko, Amano, Yasushi, Suzuki, Tomoyuki, Mori, Masamichi, Yoshida, Taku
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817455/
https://ncbi.nlm.nih.gov/pubmed/31692922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27222
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