Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells

Therapeutic effects of FLT3 inhibitors have been reported in acute myeloid leukemia (AML) with constitutively activating FLT3 mutations, including internal tandem duplication (ITD) and point mutation, which are found in approximately one-third of AML patients. One of the critical issues of treatment...

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Vydáno v:Oncotarget
Hlavní autoři: Kawase, Tatsuya, Nakazawa, Taisuke, Eguchi, Tomohiro, Tsuzuki, Hirofumi, Ueno, Yoko, Amano, Yasushi, Suzuki, Tomoyuki, Mori, Masamichi, Yoshida, Taku
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817455/
https://ncbi.nlm.nih.gov/pubmed/31692922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27222
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