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Interaction of the tetratricopeptide repeat domain of aryl hydrocarbon receptor–interacting protein–like 1 with the regulatory Pγ subunit of phosphodiesterase 6

Phosphodiesterase-6 (PDE6) is key to both phototransduction and health of rods and cones. Proper folding of PDE6 relies on the chaperone activity of aryl hydrocarbon receptor–interacting protein–like 1 (AIPL1), and mutations in both PDE6 and AIPL1 can cause a severe form of blindness. Although AIPL1...

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Vydáno v:J Biol Chem
Hlavní autoři: Yadav, Ravi P., Boyd, Kimberly, Yu, Liping, Artemyev, Nikolai O.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816093/
https://ncbi.nlm.nih.gov/pubmed/31488544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010666
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