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Elevated hsa‐miR‐590‐3p expression down‐regulates HMGB2 expression and contributes to the severity of IgA nephropathy

Peripheral blood mononuclear cells (PBMCs) play important roles in the pathogenesis of IgA nephropathy (IgAN). Our study aimed to provide a deep understanding of IgAN and focused on the dysregulation of hsa‐miR‐590‐3p and its target gene HMGB2 in PBMCs. Three gene expression profile datasets (GSE147...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhai, Yaling, Qi, Yuanyuan, Long, Xiaoqing, Dou, Yanna, Liu, Dong, Cheng, Genyang, Xiao, Jing, Liu, Zhangsuo, Zhao, Zhanzheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815813/
https://ncbi.nlm.nih.gov/pubmed/31557418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14582
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