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Renal miR-148b is associated with megalin down-regulation in IgA nephropathy

Megalin is essential for proximal tubule reabsorption of filtered proteins, hormones, and vitamins, and its dysfunction has been reported in IgA nephropathy (IgAN). miR-148b has been shown to regulate renal megalin expression in vitro and in animal models of kidney disease. We examined a potential r...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Wen, Lu, Zhao, Zhanzheng, Xiao, Jing, Wang, Zheng, He, Xiangfei, Birn, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239259/
https://ncbi.nlm.nih.gov/pubmed/30355654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181578
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