Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis

Osteoarthritis (OA) is an age-related degenerative disease with complicated pathology involving chondrocyte apoptosis and extracellular matrix (ECM) degradation. Previous studies have shown that moderate autophagy has a protective effect against apoptosis in chondrocyte. Mangiferin is a natural poly...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Li, Yao, Wu, Yaosen, Jiang, Kaixia, Han, Wen, Zhang, Jing, Xie, Lin, Liu, Yanlong, Xiao, Jian, Wang, Xiangyang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815628/
https://ncbi.nlm.nih.gov/pubmed/31885823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8783197
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