Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation

The cellular and molecular mechanisms underlying loss of muscle mass with age (sarcopenia) are not well-understood; however, heterochronic parabiosis experiments show that circulating factors are likely to play a role. Kynurenine (KYN) is a circulating tryptophan metabolite that is known to increase...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Kaiser, Helen, Yu, Kanglun, Pandya, Chirayu, Mendhe, Bharati, Isales, Carlos M., McGee-Lawrence, Meghan E., Johnson, Maribeth, Fulzele, Sadanand, Hamrick, Mark W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815546/
https://ncbi.nlm.nih.gov/pubmed/31737181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9894238
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