Caricamento...
Late-stage trifluoromethylthiolation of benzylic C-H bonds
The benzylic positions in drugs are sites that readily react with cytochrome P450 oxidases via single-electron oxidation. New synthetic methodologies to incorporate a fluoroalkyl group at the benzylic site are continually being developed, and in this paper, we report a metal-free and site-selective...
Salvato in:
| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814834/ https://ncbi.nlm.nih.gov/pubmed/31653853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12844-9 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|