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MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion

Unraveling the mechanisms that govern the formation and function of invadopodia is essential towards the prevention of cancer spread. Here, we characterize the ultrastructural organization, dynamics and mechanical properties of collagenotytic invadopodia forming at the interface between breast cance...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ferrari, Robin, Martin, Gaëlle, Tagit, Oya, Guichard, Alan, Cambi, Alessandra, Voituriez, Raphaël, Vassilopoulos, Stéphane, Chavrier, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814785/
https://ncbi.nlm.nih.gov/pubmed/31653854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12930-y
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