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MT1-MMP: Endosomal delivery drives breast cancer metastasis

The membrane-tethered membrane type 1–matrix metalloproteinase (MT1-MMP) mediates proteolysis-based invasive tumor growth. In this issue, Marchesin et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506002) describe a tug-of-war mechanism regulating dynein and kinesin motors to drive endos...

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Publicat a:J Cell Biol
Autor principal: Linder, Stefan
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621844/
https://ncbi.nlm.nih.gov/pubmed/26504163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201510009
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