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MT1-MMP: Endosomal delivery drives breast cancer metastasis
The membrane-tethered membrane type 1–matrix metalloproteinase (MT1-MMP) mediates proteolysis-based invasive tumor growth. In this issue, Marchesin et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506002) describe a tug-of-war mechanism regulating dynein and kinesin motors to drive endos...
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| Published in: | J Cell Biol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621844/ https://ncbi.nlm.nih.gov/pubmed/26504163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201510009 |
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