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Tau deposition is associated with functional isolation of the hippocampus in aging

The tau protein aggregates in aging and Alzheimer disease and may lead to memory loss through disruption of medial temporal lobe (MTL)-dependent memory systems. Here, we investigated tau-mediated mechanisms of hippocampal dysfunction that underlie the expression of episodic memory decline using fMRI...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Harrison, Theresa M., Maass, Anne, Adams, Jenna N., Du, Richard, Baker, Suzanne L., Jagust, William J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814780/
https://ncbi.nlm.nih.gov/pubmed/31653847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12921-z
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