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Tau deposition is associated with functional isolation of the hippocampus in aging

The tau protein aggregates in aging and Alzheimer disease and may lead to memory loss through disruption of medial temporal lobe (MTL)-dependent memory systems. Here, we investigated tau-mediated mechanisms of hippocampal dysfunction that underlie the expression of episodic memory decline using fMRI...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Harrison, Theresa M., Maass, Anne, Adams, Jenna N., Du, Richard, Baker, Suzanne L., Jagust, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814780/
https://ncbi.nlm.nih.gov/pubmed/31653847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12921-z
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